Every trading asset has different trading hours, and margin requirements. Make sure to know them. To review updated specifications: Go to MT5, right-click on a symbol on the market watch window --> specification.
During periods of standard market fluctuations, major currency pairs like EUR/USD, GBP/USD, USD/JPY sell from 0.2 pips to 0.9 pips, and the commission rate is set at $4 per Standard Lot, round trip. Overnight swap fees are collected and/or paid nightly.
More information available under asset specification